Invited lecture "Physiological and Cognitive Aspects of Long-range Temporal Correlations in Neuronal Oscillations" by Nikulin Vadim - University Medicine, Berlin
Compared to the spatial synchronization, temporal dynamics of neuronal oscillations only recently gained a widespread attention in neuroscience. A particularly important and interesting discovery was a demonstration of Long-Range Temporal Correlations (LRTC) in the amplitude dynamics of neuronal oscillations. LRTC indicate that the autocorrelation of amplitude envelopes decays very slowly, according to a power-law, which in turn indicates that the past neuronal activation has a capacity to affect a future neuronal recruitment. In our studies we showed that LRTC in the amplitude dynamics of neuronal oscillations can extend to tens and even hundreds of seconds. A presence of LRTC in the human brain might indicate that the brain operates at a metastable state, which was theoretically shown to be beneficial for the optimal brain processing. This metastable state might be viewed as a delicate balance between excitation and inhibition. In my talk I will review studies showing a behavioral relevance of LRTC for cognitive and motor activities. Moreover, I will show that LRTC can serve as clinical biomarkers reliably describing pathological neuronal activations in Schizophrenia, Alzheimer and Parkinson’s Disease.
Invited lecture "Physiological and Cognitive Aspects of Long-range Temporal Correlations in Neuronal Oscillations"
Nikulin Vadim
14-00, 16 -01- 2013
room 104, 46B Volgogradskiy Prospekt, Moscow
-Department of Neurology, Charité - University Medicine Berlin, Germany
-Department of Psychology, Higher School of Economics, Moscow, Russia
Compared to the spatial synchronization, temporal dynamics of neuronal oscillations only recently gained a widespread attention in neuroscience. A particularly important and interesting discovery was a demonstration of Long-Range Temporal Correlations (LRTC) in the amplitude dynamics of neuronal oscillations. LRTC indicate that the autocorrelation of amplitude envelopes decays very slowly, according to a power-law, which in turn indicates that the past neuronal activation has a capacity to affect a future neuronal recruitment. In our studies we showed that LRTC in the amplitude dynamics of neuronal oscillations can extend to tens and even hundreds of seconds. A presence of LRTC in the human brain might indicate that the brain operates at a metastable state, which was theoretically shown to be beneficial for the optimal brain processing. This metastable state might be viewed as a delicate balance between excitation and inhibition. In my talk I will review studies showing a behavioral relevance of LRTC for cognitive and motor activities. Moreover, I will show that LRTC can serve as clinical biomarkers reliably describing pathological neuronal activations in Schizophrenia, Alzheimer and Parkinson’s Disease.